3DKUBE™ 3D Cell Culture Plasticware

Click on a topic to learn more about 3DKUBE™ 3D Cell Culture Plasticware.

Patent #D658,306; Additional U.S. & Foreign Patents Pending

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Independent Chambers (BUY NOW!)
Model 3D020

Solid gasket insert - medical grade silicone
n=2 independent sample replicates
Single cell type or mixed co-culture

Segregated Co-culture (BUY NOW!)
Model 3D010

Gasket-membrane insert
0.45 µm porosity polyethersulfone membrane
Segregated analysis of cell populations
Interaction through soluble factor transfer (green)
Valves used to direct flow across the membrane
Advanced 3D co-culture models for drug discovery

Cell Migration (BUY NOW!)
Model 3D030

Gasket-membrane insert
8.0 µm porosity polycarbonate membrane
Chamber-to-chamber cell migration (blue)
Advanced 3D co-culture models for metastasis, invasion and chemotaxis studies

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The following image depicts multiple closed perfusion flow circuit replicates using a multi-syringe pump with 3DKUBE™ 3D Cell Culture Plasticware. A variety of pumping mechanisms (i.e., peristaltic, syringe, gravity) can be used to perfuse the 3D cell-scaffold construct contained within the culture chambers. Common luer connectors, stopcock valves and tubing can be used to customize the perfusion flow circuit to accommodate the desired experimental protocol.

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(Click thumbnail for larger image)

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● General User Guide

● In Situ Imaging User Guide

● In Situ Biochemical Assays User Guide

● In Situ Histology Embedding User Guide

● Perfusion Flow Circuit Common Parts List

● Frequently Asked Questions (FAQ)

● Tech Review - "Novel Plasticware for 3D Cell Co-culture"

● Tech Review - "3D Cell Culture in situ Histological Embedding"

● Tech Review - "Cell Viability in 3D Culture using in situ Bioluminescence"

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