Do you want to test the improvement of cell functionality in 3D?

Is there a tissue you need to model that requires a second segregated cell type? 

Are you intrigued by the higher fidelity of 3D cell culture but unsure of the investment? 

Contract Testing Services

KIYATEC is pleased to offer Testing Services to address your needs.  We have extensive experience implementing perfused 3D cell culture using our 3DKUBE™ technology platform.  KIYATEC can develop tests and assays using various cell types, including primary cells and/or immortalized cell lines.

What KIYATEC Testing Services could do for you:

• Evaluate cell response to your biomaterial or 3D scaffold

  • Measurements may include cell viability, morphology, function

• Assess the biocompatibility effects of a change in material processing

  • Measurements may include toxicity, morphology, response to stimuli

• Evaluate changes in cell functionality in response to a panel of materials and 2D culture

  • Measurements may include gene expression, response to stimuli, enzyme activity

• Selection of cell type for a fixed 3D scaffold material

  • Measurements may include cell quantity, viability, function

• Selection of 3D scaffold material for a fixed cell type

  • Measurements may include seeding density and growth curve evaluation

• Research scale development and optimization of biomanufacturing processes

Contract Development Services

KIYATEC 3D Cell-based Assays

Increasingly complex models of human physiology, including cell proliferation, function, and differentiation, require cytokine and metabolic soluble factor exchange from one cell type to another.  This complexity is achieved in vitro by co-culturing two different cell types.

For many co-culture applications, mixed co-culture (two or more cell types cultured in the same chamber) has significant drawbacks, including population ratio imbalance over time due to differing proliferation rates and the challenges of downstream isolation of the target cell type of interest (e.g., for use in cell therapy).

The solution is segregated co-culture, in which two cell types are in biochemical communication but remain physically separated.  The power of segregated co-culture to build complexity into biological models and biomanufacturing is enormous but has been largely inaccessible due to technical challenges.  KIYATEC’s 3DKUBE™ technology platform unlocks the power of segregated co-culture in 3D cell culture.

If you have a technically challenging in vitro cell culture model that requires multiple cell types, please contact us to inquire.

KIYATEC Customer Service

customer.service@kiyatec.com